(clinical trial[pt] OR clinical trial*[all] OR phase trial*[all] OR phase 1 trial*[all] OR phase i trial*[all] OR phase 2 trial*[all] OR phase ii trial*[all] OR phase 3 trial*[all] OR phase iii trial*[all] OR phase 4 trial*[all] OR phase iv trial*[all] OR phase stud*[all] OR phase 1 stud*[all] OR phase i stud*[all] OR phase 2 stud*[all] OR phase ii stud*[all] OR phase 3 stud*[all] OR phase iii stud*[all] OR phase 4 stud*[all] OR phase iv stud*[all] OR multicenter study[pt] OR multicentre stud*[all] OR multicenter stud*[all] OR multicentre trial*[all] OR multicenter trial*[all] OR randomized controlled trial*[all] OR randomised controlled trial*[all] OR random allocation[mh] OR random allocation*[all] OR rct[all] OR rcts[all])